500 years before Jesus Christ, the seacoast was occupied by the Amerindians who came from the southern Caribbean or from the Greater Antilles. This spin off of settlements was due to the migration of the pre-Columbian people migrating from Central America. From the end of the 15th century, under the rule of the Kingdom of Spain, Taitos, Callinagos, Arawaks and the Caribs followed each other, until 1660 when they were forced to leave for other islands in accordance with the Franco-Spanish treaty.
Beginning 1635 with the arrival of the French and during the 17th century, the village was called PORTLAND. The principal part of the city was located on the actual site of "Autre Bord , towards the east. During the 18th century, the city became the stronghold for colonial aristocracy and the center moved to the left bank of river Audoin. This was thanks to the development of sugar cane and for a better placement of the port on the Atlantic Ocean. A lot of important construction took place to protect and improve the city, one of which was a breakwater ("mole" in French) that gave the city its new name, Le Moule, that became Guadeloupe's main commercial port. On September 20, 1828, Le Moule received rights to export its commodities to the metropolitan France without going through Pointe ŕ Pitre. Thus having direct contact with French territory, it became a target for the British fleet during the Napoleon war at the beginning of the 19th century. The heroic battle of 1809 remains a historic date for Guadeloupe.
 
In practice, all sugar cane, sugar and rum produced in Grande Terre were shipped from Le Moule's port. Consequently, the city enjoyed a flourishing commerce that was further supplemented by shipments of coffee, cotton, fertilizer, coal, building material and spare parts.
 
During the 19th century with its numerous refineries and plantations (at first about thirty then about one hundred) the planters lived a self-sufficient life style farming sugar cane, coffee, cotton, cocoa, spices and other essential food product, thus dominating Guadeloupean economics during the 1850's. After this date, they experienced many financial collapses because of failed crops, abolition of slavery, the production of bette sugar in Europe and the very strict "colonial pact". Shared farming has become necessary as well as industrial modernization and steam machines replaced traditional windmills. The sugar crises forced a new decision. In 1901, only 4 refineries survived: Duchassaing, Zévallos, Marly and Gardel. Le Moule's port lost its place of dominance to Pointe ŕ Pitre, the center of commerce shifted and the city fell into solitude.
 

The devastating cyclone of 1928 was the sounding force and the point of return for the community. The city not only rose from its ruins thanks to Mayor Charles ROMANA, but it also constructed new buildings: the townhouse, schools, churches, roads and parks.
 
Le Moule's history, the richest on the Island, enabled it to maintain many remains and relics and to develop centers of interest around them, that carry the visitor into a past full of emotion.